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What is Accutane?
Drug: |
Accutane / Isotretinoin |
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30-360 pills / 5-40 mg |
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Accutane
Isotretinoin (generic Accutane, Roaccutane) - a drug related to vitamin A, used in the treatment of certain cancers and severe forms of acne. Because of the ability of the main substance to kill rapidly dividing cells, it was originally used in chemotherapy of brain, pancreatic and several other types of cancer. It was subsequently found the ability of Accutane to inhibit excessive growth of epithelial cells of excretory ducts of the sebaceous glands, which leads to a decrease in sebum production and, consequently, to an effective cure of acne and pimples.
Currently Accutane - is one of the few drugs, the use of which leads to sustainable cure of acne and pimples in all cases.
What are the methods of acne treatment?
There are several stages of acne and, each of them has its own method of treatment. The severity of the disease can define only a dermatologist, so prior to treatment, you should consult an experienced professional. If the disease is at an early stage, it can be cured by simple procedures, such as anti-inflammatory and exfoliating.
Consider the most common treatments for this disease.
The first is cleansing or exfoliating. When cleaning facial skin is cleaned by hand or by using a special device. During the procedure, the dead skin cells are sloughed off, the skin gets rid of surface contamination and clogging of pores and cleans inflammatory comedones.
Microdermabrasion or skin resurfacing - a kind of mechanical exfoliation, in which, the top layer of the skin is gradually erased. This method gives excellent results very quickly. It will take a few sessions of this procedure, in order to improve facial skin markedly. Polishing should be conducted both: during acne and during post-acne.
Mesotherapy involves the implementation of the treatment solution with a needle in the middle part of the skin. Thus there is a deep cleansing and nourishing. Mesotherapy eliminates the disease and provide long-term effects.
Photo-therapy is the newest way to fight acne, which removes dead skin cells with flashlights. The light at the same time causes an increase in the production of collagen, the skin is tightened and deeply cleansed.
Other methods in the treatment of this disease are hydro, ozone therapy, peels and medical treatment with the help of Accutane. Method of treatment is chosen by the doctor, according to the stage of the disease.
Accutane precautions: information for women
Accutane is teratogenic drug. When the drug is assigned to a women of childbearing age, she should avoid pregnancy for two weeks before treatment. But the drug does not stay long in the tissues, so in 1-2 months after treatment, pregnancy is not prohibited. Misconception of some gynecologists and other specialists, who do not recommend to become pregnant the whole first year after treatment with Accutane: the level of drug in the blood returns to the normal physiological range in two weeks after discontinuation of therapy.
And for men, Accutane, in terms of childbearing, has no contraindications, as no effect on sperm.
All women of childbearing age, receiving Accutane, should be ready to use contraception and, if necessary, be tested for pregnancy before they start taking meds, as well as to sign a consent, which highlights the importance of avoiding pregnancy during treatment and for 4-6 weeks after its end.
Accutane benefits: why do patients prefer it?
The last word in the external treatment of acne is Accutane in a form of ointment. After 14 days of use there is a significant improvement of the skin, reduced inflammation, skin becomes healthier.
Accutane is suitable for both dry and oily skin. It does not irritate the skin, contains no shine and color. Sometimes, when using this cream, you may notice dry skin, but usually this phenomenon is weak and does not require discontinuation of therapy.
The formulation contains zinc, which is an inflammatory component, able to inhibit the production of sebum. Isotretinoin - the main active ingredient of the medication, successfully fights the bacteria, that contribute to acne formation.
Virtually, Accutane has no contraindications, so it can be used by a large number of patients, including adolescents. When using Accutane cream, you can easy use makeup, as the drug is applied in the morning after washing and before make-up, as well as in the evening after make-up removal. When using this lotion, you can stay in the sun. The only contraindication - allergy to the components of the cream.
You need to be patient, as the process of acne treating is long.
However, keeping all the rules of Accutane intake, proper care of the skin and with proper nutrition, acne will leave you sooner or later. After two months of treatment, many patients inform about great improvements of skin condition.
Accutane application in children
Accutane is not designed for acne treatment in children. In order to cure acne at your child, turn to the skin specialist and follow his further recommendations. Usually, children are prescribed more soft remedies in such cases.
Accutane release forms
- Capsules, containing 2.5, 5, 10, or 20 mg of isotretinoin
- Accutane cream
Is it possible to buy Accutane without prescription and where?
Acne - a chronic skin disease, mainly affecting the face, back, chest, which causes severe cosmetic defect. This in turn, leads to inhibition of psycho-emotional sphere of the patient. The disease is difficult to treat and requires complex therapy.
Accutane, created on the basis of the unique composition of minerals, gives a good therapeutic effect and can be bought without prescription at numerous online pharmacies. Let’s see some details.
Today the market of cosmetic products represents a fairly wide range of specially designed therapeutic remedies, that are quite effective if properly applied and could eliminate this skin problem like acne. Even if after this disease are traces on the face in the form of scars, thanks to the arsenal of modern cosmetology equipment: laser, facial resurfacing, photo-cleaning, etc, all of this can be removed and the person’s face will again be smooth, clean and silky.
Accutane is a modern effective remedy for acne, which is characterized by a high frequency and the resistance of the positive result, and is more effective and safe than antibiotics.
Accutane may be appointed by a doctor - clearly follow the instructions and recommendations in the treatment process. Thus, in some countries, the drug is available only according to prescription. But with the wide network of online shops, it’s not a problem to buy Accutane without prescription and for cheaper price.
Accutane for sale is the best and effective remedy for acne, which has the following actions:
- anti-inflammatory
- sebo-regulating
- ectylotic
Depending on the severity of disease, the course can be extended to 6 months.
The skin changes already in the process of treatment!
- no skin greasiness!
- no itching!
- no inflammation!
- yes healthy look!
Buy Accutane and shine like a star again!
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How to take Accutane: dosage and recommendations
Dosage and administration of Accutane is picked up individually for every person, depending on disease severity, age, health condition, etc. Although, Accutane is quite safe and well tolerated medicine, it should be taken under dermatologist control, which usually and set the dose.
But, if you decided to conduct self treatment, there are some standard recommendations about dosage and intake of this remedy.
To begin with, Accutane is taken:
- inside
- rectally
- externally
How to take Accutane inside?
If you are prescribed inside treatment, take the drug during meals twice a day. The therapeutic efficacy of Accutane and its side effects are dose dependent and vary in different patients. This requires individual dose adjustment during treatment.
Patients begin Accutane treatment with a dose of 0.5 mg / kg per day. In some of them, the dose ranges from 0.5 to 1.0 mg / kg body weight per day. Patients with very severe disease or body acne may require higher daily doses - up to 2.0 mg / kg. It is proved that the frequency of remission and relapse prevention are optimal for using the course dose 120 -150 mg / kg (per treatment), so the length therapy for individual patients varies depending on the daily dose.
Complete remission of acne can often be achieved at 16-24 weeks of treatment.
Most patients notice complete acne disappearance after a single course of treatment. At apparent relapse, the doctor may prescribe a second course of treatment with Accutane in the same daily doses. Since improvement may continue for up to 8 weeks after discontinuation of drug, a second course should be administered no earlier than at the end of that period.
In patients with severe renal insufficiency treatment should be started at a lower dose (e.g. , 10 mg / day ) and then increased to 1 mg / kg / day.
How to take Accutane rectally?
Rectal Accutane is taken in 0.5-1 mg / kg, 1 time a day (at night).
External use of Accutane
When acne and rosacea, apply a thin layer of Accutane ointment 2 times a day on previously cleaned areas of the skin. Duration of treatment - 4-12 weeks. A second course is possible after consultation with the doctor.
Is it possible to overdose with Accutane?
In spite of the low toxicity of isotretinoin, accidental overdose may be noticed in a form of hypervitaminosis A. These symptoms are reversible. However, in the first few hours of the onset of overdose symptoms (usually at internal use of the drug), the patient may need a gastric lavage.
Accutane and other drugs interaction
The simultaneous use of isotretinoin with other retinoids (including acitretin, tretinoin, retinol, adapalene) increases the risk of hypervitaminosis A. Because tetracyclines increase the risk of increased intracranial pressure, the simultaneous application of Accutane is contraindicated.
Accutane can weaken the effect of progesterone, so don’t use contraceptives, containing low doses of progesterone, while treatment course.
The simultaneous use of drugs, that increase photosensitivity (including sulfonamides, tetracyclines, thiazide diuretics) increases the risk of sunburn.
Side effects of Accutane: how to avoid them
There is no drug, which is free of side effects. Even the less harmful can cause at least diarrhea or headache or allergic reaction.
Accutane has its own side effects, which have been revealed during numerous clinical studies of the drug. In most cases, their development depends upon dose. Usually at the right dosing regimen tolerability of isotretinoin (given the severity of the disease) is satisfactory.
More often, there are symptoms, caused by hypervitaminosis A, i.e., dryness of mucous membranes, the severity of which (such as the lips) can be reduced by using a fatty ointment.
Dryness of mucous membranes of the nose can cause nosebleeds and dry mucous membranes of the pharynx and larynx - hoarseness.
Dry eye may lead to the development of conjunctivitis and reversible opacities. The phenomena of conjunctivitis is reduced when applying special ointment for the eyes. Because of intolerance to contact lenses during treatment, a patient must wear glasses. In rare cases, patients may experience photosensitivity reactions.
There are separate cases of occurrence of photophobia, impaired dark adaptation (reducing the severity of twilight) and the development of cataracts and vasculitis (such as Wegener's granulomatosis), anemia and neutropenia, thrombocytopenia, increased erythrocyte sedimentation rate.
Furthermore, intake of Accutane may develop a skin rash, itching, dermatitis of the face, sweating, pyogenic granuloma, nail dystrophy and increased proliferation of granulation tissue.
There are reports of rare cases of thinning hair. Observed and reversible hair loss, as well as fulminant form of acne, hirsutism, hyperpigmentation (on the face), myalgia and arthralgia, and, at least - an inflammatory bowel disease (colitis, ileitis, bleeding), hyperuricemia, mental disorders and disorders of the central nervous system (depression, seizures).
Changes in bone and hyperostosis (premature epiphyseal ossification) were observed in children and adults who received Accutane during a long period of time at high doses.
Every new patient with acne should remember that the use of Accutane is indicated only in severe forms of the disease. It was informed about benign intracranial hypertension and visual disturbances, sometimes - nausea and headache.
Most changes do not go beyond the limits of normal values during treatment and returned to baseline indicators.
As one of side effects, there have also been an increased concentration of triglycerides and cholesterol in serum and decrease in HDL levels, particularly when receiving high doses of isotretinoin, as well as in patients with a family history of lipid metabolism, diabetes, obesity and alcoholism. These changes are also dose-dependent and reversed after dose reduction or discontinuation of treatment.
Every patient should be warn about the possibility of side effects.
For more information about Accutane and its side effects - turn to the pharmacist or dermatologist. [https://www.heartofrichmond.com]
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